This detection rule identifies modifications to the Windows registry that disable the Control Panel. Such modifications typically indicate malicious behavior as they prevent users from accessing control settings, which can hinder the ability to remove malware or malicious changes. The rule monitors specific registry keys related to the Control Panel's accessibility and triggers alerts when the value of 'NoControlPanel' is set to '1'. This activity is significant as it is a tactic often employed by malware to maintain persistence on infected systems by blocking users from initiating any corrective action through traditional Windows controls. The rule utilizes data from Sysmon to track changes and is most effective in environments where registry modifications are closely monitored. Organizations should ensure that Endpoint.Registry data is being collected to utilize this detection effectively.